Social relationships and their impact on health‐related quality of life in a long‐term breast cancer survivor cohort

Author:

Belau Matthias Hans1ORCID,Jung Lisa1,Maurer Tabea23,Obi Nadia14,Behrens Sabine5,Seibold Petra5,Becher Heiko6,Chang‐Claude Jenny25

Affiliation:

1. Institute of Medical Biometry and Epidemiology University Medical Center Hamburg‐Eppendorf Hamburg Germany

2. Cancer Epidemiology University Medical Center Hamburg‐Eppendorf University Cancer Center Hamburg Hamburg Germany

3. Department of Medical Psychology University Medical Center Hamburg‐Eppendorf Hamburg Germany

4. Institute for Occupational and Maritime Medicine University Medical Center Hamburg‐Eppendorf Hamburg Germany

5. Division of Cancer Epidemiology German Cancer Research Center Heidelberg Germany

6. Heidelberg Institute of Global Health University Hospital Heidelberg Heidelberg Germany

Abstract

AbstractBackgroundHealth‐related quality of life (HRQOL) has become increasingly important for breast cancer survivors, but clinically relevant declines often persist for many years after treatment. This study aimed to investigate whether social relationships can mitigate or prevent this decline in HRQOL.MethodsData were used from the German population‐based Mamma Carcinoma Risk Factor Investigation (MARIE) cohort of 2022 breast cancer cases with follow‐up information for more than 15 years after diagnosis. Correlations between social integration, social support, and global health status (GHS) as an overall measure of HRQOL were analyzed, and linear regression analysis was performed with structural equation modeling.ResultsThe majority of participants reported high levels of social integration and social support and moderate levels of GHS. Social integration 5 years after diagnosis was associated with GHS 5 years after diagnosis (β = 1.12; 95% CI, 0.25–1.99), but no longitudinal effects were found. Social support 5 years after diagnosis was associated with better GHS 5 years (β = 0.42; 95% CI, 0.36–0.48) and 10 years after diagnosis (β = 0.12; 95% CI, 0.02–0.22), whereas social support 10 years after diagnosis was associated with GHS 10 years (β = 0.29; 95% CI, 0.20–0.39) and 15 years after diagnosis (β = 0.10; 95% CI, 0.01–0.21).ConclusionsThese results confirm that social relationships positively influence HRQOL in long‐term breast cancer survivors and that their association should receive more attention clinically and beyond routine care.

Publisher

Wiley

Reference35 articles.

1. Current and future burden of breast cancer: Global statistics for 2020 and 2040

2. Global incidence and mortality of breast cancer: a trend analysis

3. Breast Cancer.Centre for Cancer Registry Data (ZfKD).2022. Accessed October 24 2023.https://www.krebsdaten.de/Krebs/EN/Content/Cancer_sites/Breast_cancer/breast_cancer_node.html

4. Long‐Term Effects of Breast Cancer Surgery, Treatment, and Survivor Care

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