Pediatric splenic infarction: Assessment of associated clinical conditions and outcome

Author:

Grishin Evgeny1ORCID,Soudack Michalle12,Levy‐Mendelovich Sarina134,Bezalel Yael15,Lubetsky Aharon13,Cohen Omri13,Brutman‐Barazani Tami13,Efros Orly13,Kenet Gili13,Barg Assaf A.136ORCID

Affiliation:

1. Faculty of Medicine Tel Aviv University Tel Aviv Israel

2. Pediatric Imaging Unit Sheba Medical Center Ramat Gan Israel

3. National Hemophilia Center, Coagulation Unit and Amalia Biron Research Institute of Thrombosis and Hemostasis Sheba Medical Center Ramat Gan Israel

4. Talpiot Sheba Leadership Program Sheba Medical Center Ramat Gan Israel

5. Pediatric Pulmonology and National CF Center, Edmond and Lily Safra Children's Hospital Sheba Medical Center Tel‐Hashomer Israel

6. Departmnet of Pediatric Hematology‐Oncology The Edmond and Lily Safra Children's Hospital, Sheba Medical Center Ramat Gan Israel

Abstract

AbstractPediatric splenic infarction (SI) is rare yet clinically significant. Publications regarding this complication are mostly limited to case reports. This is a retrospective study examining SI etiology, clinical presentation, management, and outcomes among children. Twenty‐two patients (median age: 7.9 years) were included, mostly with pre‐existing hematological diseases. Splenomegaly (72%), thrombocytopenia, and anemia were common. Most of the patients did not receive antithrombotic therapy yet only two patients experienced recurrences. During follow up 36% of patients died, however no fatalities were attributed to thrombotic or bleeding complications.

Publisher

Wiley

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