Durable complete response to PET‐CT driven stereotactic radiation therapy plus pembrolizumab for pleomorphic Pancoast cancer: Case report and literature review

Author:

Castelluccia Alessandra1ORCID,Sardaro Angela2,Niccoli Asabella Artor3,Pisani Antonio Rosario3,Rubini Dino4,Portaluri Maurizio1,Tramacere Francesco1

Affiliation:

1. Department of Radiotherapy “A. Perrino” Hospital Brindisi Italy

2. Section of Radiology and Radiation Oncology, Interdisciplinary Department of Medicine University of Bari “Aldo Moro” Bari Italy

3. Section of Nuclear Medicine, Interdisciplinary Department of Medicine University of Bari Aldo Moro Bari Italy

4. Department of Precision Medicine Università degli Studi della Campania Luigi Vanvitelli Napoli Campania Italy

Abstract

Key Clinical MessagePET‐driven SBRT plus pembrolizumab as first‐line therapy against pleomorphic Pancoast cancer appears beneficial, probably due to high equivalent doses of SBRT on photopenic necrotic core and synergic immune system stimulation of immunoradiotherapy.

Publisher

Wiley

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