Fibrodysplasia ossificans progressiva-Reference-Cited by-同舟云学术

Fibrodysplasia ossificans progressiva

Published:2023-11 Issue:11 Volume:11 Page:
ISSN:2050-0904
Container-title:Clinical Case Reports
language:en
Short-container-title:Clinical Case Reports

Author:

Smit Chané¹^ORCID,Uys André²^ORCID

Affiliation:

1. Department of Oral and Maxillofacial Pathology, School of Dentistry University of Pretoria Pretoria South Africa

2. Department of Anatomy, School of Medicine University of Pretoria Pretoria South Africa

Abstract

Key Clinical MessageFibrodysplasia ossificans progressiva is a progressively debilitating condition associated with significant morbidity caused by heterotopic ossification. Recognition of the early signs of hallux valgus and painful soft tissue nodules can assist in the early diagnosis of this condition. Periodic radiographic examination is mandatory to monitor the disease progression.AbstractFibrodysplasia ossificans progressiva is a rare condition with an estimated prevalence of one in two million individuals. The condition is characterized by widespread heterotrophic ossification of skeletal muscles and ligaments. We report the case of an 8‐year‐old female patient and show the radiological progression of the condition.

Publisher

Wiley

Subject

General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ccr3.8165

Reference15 articles.

1. ActivinA Induced SMAD1/5 Signaling in an iPSC Derived EC Model of Fibrodysplasia Ossificans Progressiva (FOP) Can Be Rescued by the Drug Candidate Saracatinib

2. Recent progress in drug development for fibrodysplasia ossificans progressiva

3. A unique case of fibrodysplasia ossificans progressiva with anACVR1 mutation, G356D, other than the common mutation (R206H)

4. An ACVR1 R375P pathogenic variant in two families with mild fibrodysplasia ossificans progressiva

5. The Diversity of the Clinical Phenotypes in Patients With Fibrodysplasia Ossificans Progressiva