Targeting <scp>DNA</scp> topoisomerase <scp>IIα</scp> ( <scp>TOP2A</scp> ) in the hypoxic tumour microenvironment using unidirectional hypoxia‐activated prodrugs ( <scp>uHAPs</scp> )-Reference-Cited by-同舟云学术

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Targeting DNA topoisomerase IIα ( TOP2A ) in the hypoxic tumour microenvironment using unidirectional hypoxia‐activated prodrugs ( uHAPs )

Published:2022-05-02 Issue:1 Volume:75 Page:40-54
ISSN:1521-6543
Container-title:IUBMB Life
language:en
Short-container-title:IUBMB Life

Author:

Smith Paul J.¹^ORCID,McKeown Stephanie R.²,Patterson Laurence H.³

Affiliation:

1. Cancer and Genetics Division, School of Medicine Cardiff University Cardiff UK

2. Biomedical Sciences Research Institute Ulster University Coleraine UK

3. Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences University of Bradford Bradford UK

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Genetics,Molecular Biology,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/iub.2619

Reference153 articles.

1. Defining normoxia, physoxia and hypoxia in tumours—implications for treatment response

2. Role of hypoxia in cancer therapy by regulating the tumor microenvironment

3. Aspects of the Tumor Microenvironment Involved in Immune Resistance and Drug Resistance

4. The Role of Hypoxia in Glioblastoma Radiotherapy Resistance

5. The Hypoxic Microenvironment of Breast Cancer Cells Promotes Resistance in Radiation Therapy

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2. Systemic lupus erythematosus promotes HCC by promoting cell cycle C2/M transition;2023-08-10

3. In vitro radiosensitization of breast cancer with hypoxia‐activated prodrugs;Journal of Cellular and Molecular Medicine;2022-07-16

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