Tumour cell survival mechanisms in lethal metastatic prostate cancer differ between bone and soft tissue metastases

Author:

Akfirat Canan1,Zhang Xiaotun2,Ventura Aviva1,Berel Dror3,Colangelo Mary E1,Miranti Cindy K4,Krajewska Maryla5,Reed John C5,Higano Celestia S6,True Lawrence D7,Vessella Robert L28,Morrissey Colm2,Knudsen Beatrice S13

Affiliation:

1. Division of Public Health Sciences; Fred Hutchinson Cancer Research Center; Seattle WA USA

2. Department of Urology; University of Washington; Seattle WA USA

3. Cedars Sinai Medical Center; Los Angeles CA USA

4. Van Andel Research Institute; Grand Rapids MI USA

5. Sanford-Burnham Medical Research Institute; La Jolla CA USA

6. Division of Medical Oncology; University of Washington; CA USA

7. Department of Pathology; University of Washington; CA USA

8. GRECC and Research Service, Department of Veterans Affairs Medical Center; Seattle WA USA

Publisher

Wiley

Subject

Pathology and Forensic Medicine

Reference34 articles.

1. Apoptosis evasion: the role of survival pathways in prostate cancer progression and therapeutic resistance;McKenzie;J Cell Biochem,2006

2. Cell death: critical control points;Danial;Cell,2004

3. Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c;Korsmeyer;Cell Death Differ,2000

4. Elevated expression of Bcl-X and reduced Bak in primary colorectal adenocarcinomas;Krajewska;Cancer Res,1996

5. IAP proteins: blocking the road to death's door;Salvesen;Nature Rev Mol Cell Biol,2002

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