Beyond the <scp>Michaelis–Menten</scp> : Accurate Prediction of Drug Interactions Through Cytochrome <scp>P450 3A4</scp> Induction-Reference-Cited by-同舟云学术

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Beyond the Michaelis–Menten : Accurate Prediction of Drug Interactions Through Cytochrome P450 3A4 Induction

Published:2023-01-11 Issue:5 Volume:113 Page:1048-1057
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin Pharma and Therapeutics

Author:

Vu Ngoc‐Anh Thi¹^ORCID,Song Yun Min²³^ORCID,Tran Quyen Thi¹^ORCID,Yun Hwi‐yeol¹⁴^ORCID,Kim Sang Kyum¹^ORCID,Chae Jung‐woo¹⁴,Kim Jae Kyoung²³^ORCID

Affiliation:

1. College of Pharmacy Chungnam National University Daejeon Korea

2. Department of Mathematical Sciences KAIST Daejeon Korea

3. Biomedical Mathematics Group, Institute for Basic Science Daejeon Korea

4. Department of Bio‐AI convergence Chungnam National University Daejeon Korea

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.2824

Reference49 articles.

1. Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

2. CYP Induction-Mediated Drug Interactions: in Vitro Assessment and Clinical Implications

3. CORRECTION TO “A COMBINED MODEL FOR PREDICTING CYP3A4 CLINICAL NET DRUG-DRUG INTERACTION BASED ON CYP3A4 INHIBITION, INACTIVATION, AND INDUCTION DETERMINED IN VITRO”

4. Comparison of different approaches to predict metabolic drug–drug interactions

5. The Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of America

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1. Enzyme-mediated drug-drug interactions: a review of in vivo and in vitro methodologies, regulatory guidance, and translation to the clinic;Drug Metabolism Reviews;2024-07-26

2. Theory on the rate equations of Michaelis-Menten type enzyme kinetics with competitive inhibition;PLOS ONE;2024-07-18

3. Beyond homogeneity: Assessing the validity of the Michaelis–Menten rate law in spatially heterogeneous environments;PLOS Computational Biology;2024-06-06

4. The Michaelis–Menten Reaction at Low Substrate Concentrations: Pseudo-First-Order Kinetics and Conditions for Timescale Separation;Bulletin of Mathematical Biology;2024-05-04

5. Validity conditions of approximations for a target-mediated drug disposition model: A novel first-order approximation and its comparison to other approximations;PLOS Computational Biology;2024-04-24

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