Mitochondrial replacement by genome transfer in human oocytes: Efficacy, concerns, and legality
Author:
Affiliation:
1. Department of Obstetrics and Gynecology Keio University School of Medicine Tokyo Japan
2. Department of Reproductive Biology National Research Institute for Child Health and Development Tokyo Japan
Funder
Japan Society for the Promotion of Science
Publisher
Wiley
Subject
Cell Biology,Reproductive Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/rmb2.12356
Reference51 articles.
1. Nuclear genome transfer in human oocytes eliminates mitochondrial DNA variants
2. Large Variation in the Ratio of Mitochondrial to Nuclear Mutation Rate across Animals: Implications for Genetic Diversity and the Use of Mitochondrial DNA as a Molecular Marker
3. Biparental Inheritance of Mitochondrial DNA in Humans
4. Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies
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