Coupling Nanostructured Microchips with Covalent Chemistry Enables Purification of Sarcoma‐Derived Extracellular Vesicles for Downstream Functional Studies

Author:

Dong Jiantong12ORCID,Zhang Ryan Y.1ORCID,Sun Na1ORCID,Hu Junhui3ORCID,Smalley Matthew D.1ORCID,Zhou Anqi1ORCID,Hua Yue1ORCID,Rothermich Winston1,Chen Mengxiang1,Chen Jiayuan1,Ye Jinglei1,Teng Pai‐Chi1,Qi Dongping1ORCID,Toretsky Jeffrey A.4,Tomlinson James S.5,Li Mengyuan2ORCID,Weiss Paul S.6ORCID,Jonas Steven J.7ORCID,Federman Noah7,Wu Lily3ORCID,Zhao Meiping2ORCID,Tseng Hsian‐Rong1ORCID,Zhu Yazhen1ORCID

Affiliation:

1. California NanoSystems Institute Crump Institute for Molecular Imaging Department of Molecular and Medical Pharmacology University of California Los Angeles (UCLA) 570 Westwood Plaza Los Angeles CA 90095 USA

2. Beijing National Laboratory for Molecular Sciences MOE Key Laboratory of Bioorganic Chemistry and Molecular Engineering College of Chemistry and Molecular Engineering Peking University 202 Chengfu Road, Haidian District Beijing 100871 China

3. Department of Molecular and Medical Pharmacology David Geffen School of Medicine UCLA 650 Charles E Young Dr. Los Angeles CA 90095 USA

4. Departments of Oncology and Pediatrics Georgetown University 3970 Reservoir Rd NW Washington DC 20057 USA

5. Department of Surgery UCLA 200 Medical Plaza Los Angeles CA 90024 USA

6. California NanoSystems Institute Departments of Chemistry and Biochemistry Bioengineering, and Materials Science and Engineering UCLA 570 Westwood Plaza Los Angeles CA 90095 USA

7. Department of Pediatrics Ronald Reagan UCLA Medical Center UCLA Mattel Children's Hospital 10833 Le Conte Ave Los Angeles CA 90095 USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Electrochemistry,Condensed Matter Physics,Biomaterials,Electronic, Optical and Magnetic Materials

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