1. School of Pharmaceutical Sciences Wenzhou Medical University Wenzhou 325035 China
2. Department of Molecular Biomedical Sciences and Comparative Medicine Institute North Carolina State University Raleigh NC 27607 USA
3. Joint Department of Biomedical Engineering University of North Carolina at Chapel Hill and North Carolina State University Raleigh NC 27695 USA
4. Division of Cardiothoracic Surgery University of North Carolina at Chapel Hill Chapel Hill NC 27514 USA
5. Division of Cardiology University of North Carolina at Chapel Hill Chapel Hill NC 27514 USA