Pregnenolone as a potential candidate for hormone therapy for female reproductive disorders targeting ERβ

Author:

Shin Ye Young1,Kang Eun-Jin1,Jeong Jea Sic1,Kim Min Jae1,Jung Eui-Man2,Jeung Eui-Bae2,An Beum-Soo1ORCID

Affiliation:

1. Department of Biomaterials Science; College of Natural Resources and Life Science/Life and Industry Convergence Research Institute, Pusan National University; Miryang Gyeongsangnam Republic of Korea

2. Laboratory of Veterinary Biochemistry and Molecular Biology, College of Veterinary Medicine, Chungbuk National University; Cheongju Chungbuk Republic of Korea

Funder

Korea Health Industry Development Institute

Ministry of Health and Welfare

Publisher

Wiley

Subject

Cell Biology,Developmental Biology,Genetics

Reference32 articles.

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2. pS2 Gene expression in HepG2 cells: Complex regulation through crosstalk between the estrogen receptor α, an estrogen-responsive element, and the activator protein 1 response element;Barkhem;Molecular Pharmacology,2002

3. Hormone induction of progesterone receptor (PR) messenger ribonucleic acid and activation of PR promoter regions in ovarian granulosa cells: Evidence for a role of cyclic adenosine 3′, 5′-monophosphate but not estradiol;Clemens;Molecular Endocrinology,1998

4. A woman's heart;Ewer;Cancer,2009

5. Estrogen and progesterone signalling in the normal breast and its implications for cancer development;Hilton;Molecular and Cellular Endocrinology,2017

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