Advancements in dementia research, diagnostics, and care in Latin America: Highlights from the 2023 Alzheimer's Association International conference satellite symposium in Mexico City-Reference-Cited by-同舟云学术

Advancements in dementia research, diagnostics, and care in Latin America: Highlights from the 2023 Alzheimer's Association International conference satellite symposium in Mexico City

Published:2024-05-27 Issue:7 Volume:20 Page:5009-5026
ISSN:1552-5260
Container-title:Alzheimer's & Dementia
language:en
Short-container-title:Alzheimer's & Dementia

Author:

Sosa Ana Luisa¹,Brucki Sonia MD²,Crivelli Lucia³,Lopera Francisco Javier⁴,Acosta Daisy M⁵,Acosta‐Uribe Juliana⁴⁶,Aguilar Diego⁷,Aguilar‐Navarro Sara G⁸,Allegri Ricardo F⁹¹⁰,Bertolucci Paulo HF¹¹,Calandri Ismael L³,Carrillo Maria C¹²,Mendez Patricio Alexis Chrem¹³,Cornejo‐Olivas Mario¹⁴¹⁵,Custodio Nilton¹⁶¹⁷,Damian Andrés¹⁸,de Souza Leonardo Cruz¹⁹²⁰,Duran‐Aniotz Claudia²¹²²,García Adolfo M²¹²³²⁴²⁵,García‐Peña Carmen²⁶,Gonzales Mitzi M²⁷²⁸,Grinberg Lea T²⁹³⁰,Ibanez Agustin M²¹²³³¹³²³³,Illanes‐Manrique Maryenela Zaida¹⁴¹⁵²³,Jack Clifford R³⁴,Leon‐Salas Jorge Mario³⁵,Llibre‐Guerra Jorge J³⁶³⁷,Luna‐Muñoz José³⁸³⁹⁴⁰,Matallana Diana⁴¹⁴²⁴³,Miller Bruce L²³⁴⁴,Naci Lorina³¹⁴⁵,Parra Mario A⁴⁶,Pericak‐Vance Margaret⁴⁷⁴⁸,Piña‐Escudero Stefanie D²³³¹⁴⁴,França Resende Elisa de Paula²³³¹⁴⁹,Ringman John M⁵⁰,Sevlever Gustavo⁵¹,Slachevsky Andrea⁵²⁵³⁵⁴⁵⁵,Suemoto Claudia Kimie⁵⁶,Valcour Victor⁵⁷,Villegas‐Lanau Andres⁴,Yassuda Mônica S²⁵⁸,Mahinrad Simin¹²^ORCID,Sexton Claire¹²^ORCID

Affiliation:

1. Laboratorio de Demencias del Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez Mexico City CDMX México

2. Department of Neurology Cognitive and Behavioral Group University of Sao Paulo São Paulo São Paulo Brazil

3. Department of Cognitive Neurology Fleni Buenos Aires Argentina

4. Grupo de Neurociencias (GNA) Facultad de Medicina Universidad de Antioquia Medellín Colombia

5. Universidad Nacional Pedro Henriquez Urena (UNPHU) Santo Domingo Dominican Republic

6. Neuroscience Research Institute and Department of Molecular Cellular and Developmental Biology University of California Santa Barbara Santa Barbara California USA

7. Alzheimer's Disease International London UK

8. Department of Geriatrics Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran México CDMX Mexico

9. Instituto de Neurociencias Fleni Buenos Aires Argentina

10. Department of Neurosciences Universidad de la Costa CUC Barranquilla Colombia

11. Neurology & Neurosurgery Department Escola Paulista de Medicina/UNIFESP São Paulo São Paulo Brazil

12. Alzheimer's Association Chicago Illinois USA

13. Memory Center Fleni Buenos Aires Argentina

14. Neurogenetics Working Group Universidad Científica del Sur Lima Peru

15. Neurogenetics Research Center Instituto Nacional de Ciencias Neurologicas Lima Peru

16. Unidad de Diagnóstico de Deterioro Cognitivo y Prevención de Demencia Instituto Peruano de Neurociencias Lima Peru

17. Escuela Profesional de Medicina Humana Universidad Privada San Juan Bautista Lima Peru

18. Departamento de Montevideo Centro Uruguayo de Imagenología Molecular (CUDIM) and Unidad Académica de Medicina Nuclear e Imagenología Molecular Hospital de Clínicas Universidad de la República (UdelaR) Montevideo Montevideo Uruguay

19. Programa de Pós‐Graduação em Neurociências Universidade Federal de Minas Gerais (UFMG) Belo Horizonte MG Brazil

20. Departamento de Clínica Médica da Faculdade de Medicina da UFMG Belo Horizonte MG Brazil

21. Latin American Brain Health Institute (BrainLat) Universidad Adolfo Ibañez Santiago Chile

22. Center for Social and Cognitive Neuroscience (CSCN) School of Psychology Universidad Adolfo Ibañez Santiago Chile

23. Global Brain Health Institute (GBHI) University of California San Francisco (UCSF) San Francisco California USA

24. Cognitive Neuroscience Center Universidad de San Andrés Victoria Provincia de Buenos Aires Argentina

25. Departamento de Lingüística y Literatura Facultad de Humanidades Universidad de Santiago de Chile Santiago Chile

26. Instituto Nacional de Geriatría México CDMX Mexico

27. Department of Neurology Cedars Sinai Medical Center Los Angeles California USA

28. Glenn Biggs Institute UT Health San Antonio San Antonio Texas USA

29. Department of Neurology and Pathology University of California San Francisco (UCSF) San Francisco California USA

30. Department of Pathology University of Sao Paulo São Paulo São Paulo Brazil

31. Global Brain Health Institute (GBHI) University of Trinity Dublin Lloyd Building Trinity College Dublin Dublin Ireland

32. Cognitive Neuroscience Center (CNC) Universidad de San Andrés, and CONICET Victoria Argentina

33. Trinity College Dublin (TCD) College Green Dublin Ireland

34. Mayo Clinic Rochester Minnesota USA

35. Departamento de Investigación Clínica Life Science Research Institute Hospital Clinica Biblica San José Costa Rica

36. Dominantly Inherited Alzheimer's Network Trials Unit Washington University School of Medicine St. Louis Missouri USA

37. Department of Neurology Washington University School of Medicine in St.Louis St. Louis Missouri USA

38. Banco Nacional de Cerebros‐UNPHU Universidad Nacional Pedro Henríquez Ureña Santo Domingo Dominican Republic

39. National Dementia BioBank Dirección de Investigación Innovación y Posgrado Universidad Politécnica de Pachuca Zempoala México

40. Federación Mexicana de Alzheimer (FEDMA) México CDMX Mexico

41. Pontificia Universidad Javeriana Medical School Aging Institute Hospital Universitario San Ignacio Bogotá Colombia

42. Memory and Cognition Center, Intellectus Hospital Universitario San Ignacio Bogotá Colombia

43. Mental Health Department Hospital Universitario Fundación Santa Fe Bogotá Colombia

44. Department of Neurology Memory and Aging Center University of California San Francisco (UCSF) San Francisco California USA

45. Trinity College Institute of Neuroscience Trinity College Dublin College Green Dublin Ireland

46. Department of Psychological Sciences and Health University of Strathclyde Glasgow UK

47. John P Hussman Institute for Human Genomics Miller School of Medicine University of Miami Coral Gables Florida USA

48. Dr. John T Macdonald Foundation Department of Human Genetics University of Miami Miller School of Medicine Coral Gables Florida USA

49. Universidade Federal de Minas Gerais Faculdade de Medicina Ciências Médicas de Minas Gerais Hospital das Clínicas ‐ EBSERH‐UFMG Belo Horizonte Brazil

50. Department of Neurology Alzheimer's Disease Research Center Keck School of Medicine University of Southern California Los Angeles California USA

51. Department of Neuropathology Fleni Buenos Aires Argentina

52. Geroscience Center for Brain Health and Metabolism (GERO) Santiago Chile

53. Memory and Neuropsychiatric Center (CMYN) Neurology Department Hospital del Salvador & Faculty of Medicine University of Chile Santiago de Chile Chile

54. Neuropsychology and Clinical Neuroscience Laboratory (LANNEC) Physiopathology Program – Institute of Biomedical Sciences (ICBM) Neuroscience and East Neuroscience Departments Faculty of Medicine University of Chile Santiago de Chile Chile

55. Servicio de Neurología Departamento de Medicina Clínica Alemana‐Universidad del Desarrollo Las Condes Chile

56. Division of Geriatrics University of Sao Paulo Medical School São Paulo São Paulo Brazil

57. Department of Neurology University of California San Francisco (UCSF) San Francisco California USA

58. Gerontology, School of Arts Sciences and Humanities University of Sao Paulo São Paulo São Paulo Brazil

Abstract

AbstractINTRODUCTIONWhile Latin America (LatAm) is facing an increasing burden of dementia due to the rapid aging of the population, it remains underrepresented in dementia research, diagnostics, and care.METHODSIn 2023, the Alzheimer's Association hosted its eighth satellite symposium in Mexico, highlighting emerging dementia research, priorities, and challenges within LatAm.RESULTSSignificant initiatives in the region, including intracountry support, showcased their efforts in fostering national and international collaborations; genetic studies unveiled the unique genetic admixture in LatAm; researchers conducting emerging clinical trials discussed ongoing culturally specific interventions; and the urgent need to harmonize practices and studies, improve diagnosis and care, and use affordable biomarkers in the region was highlighted.DISCUSSIONThe myriad of topics discussed at the 2023 AAIC satellite symposium highlighted the growing research efforts in LatAm, providing valuable insights into dementia biology, genetics, epidemiology, treatment, and care.

Funder

Alzheimer's Association

National Institutes of Health

National Institute on Aging

Publisher

Wiley

Reference140 articles.

1. 2023 Alzheimer's disease facts and figures

2. Dementia in Latin America: Paving the way toward a regional action plan

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