Affiliation:
1. Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy Zunyi Medical University Zunyi Guizhou 563000 China
2. Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education Zunyi Medical University Zunyi 563000 China
Abstract
AbstractTwo new sesquiterpenoids, dendroaduoid A (1) and dendroaduol (2), together with four known sesquiterpenoids were isolated from the stems of Dendrobium aduncum. Their structures were identified by HR‐ESI‐MS and NMR experiments, and the complete assignments of 1H and 13C NMR data for two new sesquiterpenoids were obtained by the aid of HSQC, HMBC, 1H‐1H COSY, NOESY, and ECD techniques. The cytotoxic effects of the isolated compounds on four tumor cell lines (HCT‐116, HepG2, A549, and SW1990) were evaluated using MTT assay. Otherwise, the inhibitory activity of these six sesquiterpenoids on glycosidase was also evaluated.
Funder
Guizhou Science and Technology Department
Subject
General Materials Science,General Chemistry