1. Hepatobiliary Division, Department of Internal Medicine Kaohsiung Medical University Hospital, Kaohsiung Medical University Kaohsiung Taiwan
2. Faculty of Internal Medicine School of Medicine, College of Medicine, Kaohsiung Medical University Kaohsiung Taiwan
3. Department of Biological Science and Technology College of Biological Science and Technology, National Chiao Tung University Hsinchu Taiwan
4. Department of Chemistry National Sun Yat‐Sen University Kaohsiung Taiwan
5. Department of Internal Medicine Chi Mei Hospital, Liouying Tainan Taiwan