Therapeutic and cosmeceutical role of glycosylated natural products in dermatology

Author:

Kumar Amit123,Kaur Sarabjit2,Sangwan Pyare L.1,Tasduq Sheikh A.34ORCID

Affiliation:

1. Natural Product and Medicinal Chemistry Division CSIR‐Indian Institute of Integrative Medicine Jammu India

2. Department of Pharmaceutical Sciences Guru Nanak Dev University Amritsar Punjab India

3. PK/PD divisions CSIR‐Indian Institute of Integrative Medicine Jammu India

4. PK‐PD and Toxicology Divisions Academy of Scientific and Innovative Research (AcSIR) Ghaziabad India

Abstract

AbstractNatural products (NPs) remain the primary source of pharmacologically active candidates for drug discovery. Since time immemorial, NPs have attracted considerable attention because of their beneficial skin effects. Moreover, there has been a great interest in using such products for the cosmetics industry in the past few decades, bridging the gap between modern and traditional medicine. Terpenoids, Steroids, and Flavonoids having glycosidic attachment have proven biological effects with a positive impact on human health. NPs derived glycosides are mainly found in fruits, vegetables, and plants, and most of them have a special reverence in traditional and modern medicine for disease prevention and treatment. A literature review was performed using scientific journals, Google scholar, Scifinder, PubMED, and Google patents. These scientific articles, documents, and patents establish the significance of glycosidic NPs in the areas of dermatology. Considering the human inclination to the usage of NPs rather than synthetic or inorganic drugs (especially in the area of skin care), in the present review we have discussed the worth of NP glycosides in beauty care and skin‐related therapeutics and the mechanistic pathways involved.

Funder

Council of Scientific and Industrial Research, India

Department of Biotechnology, Ministry of Science and Technology, India

Publisher

Wiley

Subject

Pharmacology

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