Combination of insulinomimetic agents H2O2 and vanadate enhances insulin receptor mediated tyrosine phosphorylation of IRS-1 leading to IRS-1 association with the phosphatidylinositol 3-kinase
Author:
Publisher
Wiley
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference53 articles.
1. Phosphatidylinositol 3′-kinase is activated by association with IRS-1 during insulin stimulation.
2. Insulin stimulation of phosphatidylinositol 3-kinase activity maps to insulin receptor regions required for endogenous substrate phosphorylation.
3. Association of IRS-1 with the insulin receptor and the phosphatidylinositol 3'-kinase. Formation of binary and ternary signaling complexes in intact cells.
4. Binding of the Ras Activator Son of Sevenless to Insulin Receptor Substrate-1 Signaling Complexes
5. Marked Improvement of Glucose Homeostasis in Diabetic ob/ob Mice Given Oral Vanadate
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