Comparative assessment of HIF-1α and Akt responses in human lung and skin cells exposed to benzo[α]pyrene: Effect of conditioned medium from pre-exposed primary fibroblasts

Author:

Mavrofrydi Olga1,Mavroeidi Panagiota1,Papazafiri Panagiota1

Affiliation:

1. Division of Animal and Human Physiology; Department of Biology; University of Athens; 15784 Panepistimiopolis Ilissia Athens Greece

Funder

National Scholarships Foundation, Greece

Special Research Account of the University of Athens

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Management, Monitoring, Policy and Law,Toxicology,General Medicine

Reference52 articles.

1. In vivo DNA adduct formation by benzo(a)pyrene in mouse and rat epidermal and dermal fibroblasts after topical application of an initiating dose of benzo(a)pyrene;Alexandrov;Arch Geschwulstforsch,1990

2. Biologic effects induced in vitro by PM10 from three different zones of Mexico City;Alfaro-Moreno;Environ Health Perspect,2002

3. Co-cultures of multiple cell types mimic pulmonary cell communication in response to urban PM10;Alfaro-Moreno;Eur Respir J,2008

4. Hypoxia-inducible factor-1 and oncogenic signalling;Bardos;Bioessays,2004

5. Activation of AKT kinases in cancer: Implications for therapeutic targeting;Bellacosa;Adv Cancer Res,2005

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