Development and validation of an LC-MS/MS method for the determination of a novel thienoquinolin urea transporter inhibitor PU-48 in rat plasma and its application to a pharmacokinetic study-Reference-Cited by-同舟云学术

Development and validation of an LC-MS/MS method for the determination of a novel thienoquinolin urea transporter inhibitor PU-48 in rat plasma and its application to a pharmacokinetic study

Published:2017-12-22 Issue:4 Volume:32 Page:e4157
ISSN:0269-3879
Container-title:Biomedical Chromatography
language:en
Short-container-title:Biomedical Chromatography

Author:

Zhang Zhi-Yuan¹,Wang Xin¹,Liu Dan²,Zhang Hua³,Zhang Qiang³,Lu Ying-Yuan¹,Li Pu¹,Lou Ya-Qing¹,Yang Bao-Xue¹,Lu Chuang⁴,Lou Ya-Xin²,Zhang Guo-Liang¹^ORCID

Affiliation:

1. Department of Pharmacology, School of Basic Medical Sciences; Peking University; Beijing China

2. Proteomics Laboratory, Medical and Health Analysis Center; Peking University; Beijing China

3. Department of Pharmaceutics, School of Pharmaceutical Sciences; Peking University; Beijing China

4. Department of Drug Metabolism and Pharmacokinetics, Biogen; Cambridge Massachusetts USA

Funder

National Basic Research Program of China

National Natural Science Foundations of China

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/bmc.4157/fullpdf

Reference34 articles.

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2. Urea transporter proteins as targets for small-molecule diuretics;Esteva-Font;Nature Reviews Nephrology,2015

3. A small molecule screen identifies selective inhibitors of urea transporter UT-A;Esteva-Font;Chemistry & Biology,2013

4. Simultaneous determination of timosaponin B-II and A-III in rat plasma by LC-MS/MS and its application to pharmacokinetic study;Feng;Journal of Chromatography B: Analytical Technology in Biomedicine and Life Sciences,2014

5. Urinary concentrating defect in mice with selective deletion of phloretin-sensitive urea transporters in the renal collecting duct;Fenton;Proceedings of the National Academy of Sciences of the United States of America,2004

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