Rapid identification of various chemical components in Cinnamomi ramulus by UPLC‐Q‐Orbitrap‐MS

Author:

Shu Lexin1,Liu Sitong1,Zhang Fangfang1,Qiu Huixin1,Zhang Shumin1,Qian Jun1,Xu Yanyan1,Deng Yanru1,Wang Yuming1,Li Yubo1ORCID

Affiliation:

1. School of Chinese Materia Medica Tianjin University of Traditional Chinese Medicine Tianjin China

Abstract

AbstractCinnamomi ramulus (CR) is a common Chinese herbal medicine with a long history. It is often used to treat exogenous wind‐cold diseases in clinic, but its chemical compositions remain to be studied. In this study, CR was extracted with 75% ethanol, and UPLC‐Q‐Orbitrap‐MS combined with data post‐processing method was used to identify the chemical components in the extract. Through this technology, the components in CR can be separated and accurately identified. A total of 61 compounds were identified, including 14 simple phenylpropanoids, 3 coumarins, 5 lignans, 14 flavonoids, 10 benzoic acids, 8 organic acids, and 7 others. This study confirmed the existence of these compounds in CR and speculated the cleavage pathways of each compound, which enriched the mass spectrometry data and cleavage rules. This study can provide a reference for CR and other research.

Funder

National Natural Science Foundation of China

Publisher

Wiley

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