Paracetamol sensing with a flexible graphene paper electrode modified with MnCo2O4

Abstract

AbstractBACKGROUNDThe design of new‐generation flexible sensors for medical applications has gained considerable interest in the research community in recent past years. Herein, a free‐standing flexible electrode was developed for the electrochemical determination of Paracetamol (PC). This graphene‐based paper electrode was prepared using graphene and MnCo2O4 dispersion with a mold‐casting method followed by chemical reduction. The morphology and structure of our flexible paper electrode (MnCo2O4/GP) were characterized by scanning electron microscopy, energy‐dispersive, X‐ray diffraction, X‐ray photoelectron, and Raman spectroscopy.RESULTSThe as‐prepared flexible MnCo2O4/GP showed outstanding sensing performance for PC, as compared to GP, due to the excellent electrochemical properties of MnCo2O4. The proposed sensor exhibited a wide linear range of 4.64–1000 μM for electrochemical determination of PC with a low detection limit of 1.39 μM. Furthermore, MnCo2O4/GP was successfully applied for PC syrup and tablets with good accuracy results.CONCLUSIONSFor the first time, the present study demonstrated the fabrication and utilization of MnCo2O4‐modified graphene paper to develop a flexible and sensitive electrode for monitoring PC. © 2024 The Author(s). Journal of Chemical Technology and Biotechnology published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry (SCI).