Nuclear magnetic resonance-based metabolomics identifies phenylalanine as a novel predictor of incident heart failure hospitalisation: results from PROSPER and FINRISK 1997

Author:

Delles Christian1,Rankin Naomi J.12,Boachie Charles3,McConnachie Alex3,Ford Ian3,Kangas Antti4,Soininen Pasi45,Trompet Stella6,Mooijaart Simon P.6,Jukema J. Wouter6,Zannad Faiez78,Ala-Korpela Mika4591011,Salomaa Veikko12,Havulinna Aki S.1213,Welsh Paul1,Würtz Peter14,Sattar Naveed1

Affiliation:

1. Institute of Cardiovascular and Medical Sciences (ICAMS), BHF Glasgow Cardiovascular Research Centre; University of Glasgow; Glasgow UK

2. Glasgow Polyomics, Joseph Black Building; University of Glasgow; Glasgow UK

3. Robertson Centre for Biostatistics, Boyd Orr Building; University of Glasgow; Glasgow UK

4. Computational Medicine, Faculty of Medicine and Biocenter Oulu; University of Oulu; Oulu Finland

5. NMR Metabolomics Laboratory, School of Pharmacy; University of Eastern Finland; Kuopio Finland

6. Leiden University Medical Centre; Leiden The Netherlands

7. Inserm Centre d'Investigation Clinique (CIC) 1443; Université de Lorraine; Lorraine France

8. Centre Hospitalier Régional Universitaire (CHRU) de Nancy; Nancy France

9. Medical Research Council Integrative Epidemiology Unit; University of Bristol; Bristol UK

10. Population Health Science, Bristol Medical School; University of Bristol; Bristol UK

11. Systems Epidemiology; Baker Heart and Diabetes Institute; Melbourne Victoria Australia. Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences, The Alfred Hospital; Monash University; Melbourne Victoria Australia

12. National Institute for Health and Welfare (THL); Helsinki Finland

13. Institute for Molecular Medicine (FIMM); University of Helsinki; Helsinki Finland

14. Research Programs Unit, Diabetes and Obesity; University of Helsinki; Helsinki Finland

Funder

European Federation of Pharmaceutical Industries Associations (EFPIA)

Innovative Medicines Initiative Joint Undertaking

European Medical Information Framework (EMIF)

European Commission under the Health Cooperation Work Programme of the 7th Framework Programme

Oulun Yliopisto

Sigrid Juselius Foundation

Novo Nordisk Foundation

Academy of Finland

University of Bristol

UK Medical Research Council

Finnish Foundation

The Medical Research Council

The Engineering and Physical Sciences Research Council

Publisher

Wiley

Subject

Cardiology and Cardiovascular Medicine

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