Highly sensitive liquid chromatography–tandem mass spectrometry assay for the determination of azathioprine in presence of mercaptopurine and its application to a human pharmacokinetic study

Author:

Valluri Venkat Rao12,Katari Naresh Kumar1ORCID,Khatri Chirag2,Vyas Govind3,Polagani Srinivasa Rao2,Ponnam Vijetha4

Affiliation:

1. Department of Chemistry School of Science GITAM Deemed to be University Hyderabad India

2. AnaCipher Clinical Research Organization Hyderabad India

3. R&D and Regulatory Compliance Invahealth Inc. Cranbury USA

4. Vignan's Foundation for Science Technology and Research Guntur India

Publisher

Wiley

Reference17 articles.

1. https://www.medicines.org.uk/emc/product/3823/smpc(last time accessed: April 12 2021).

2. Azathioprine, 6-mercaptopurine in inflammatory bowel disease: Pharmacology, efficacy, and safety

3. https://mri.cts‐mrp.eu/Human/Downloads/DE_H_3036_001_FinalSPC_3of4.pdf(last time accessed: April 15 2021).

4. https://www.ncbi.nlm.nih.gov/books/NBK100661(last time accessed: April 18 2021)

5. https://mri.cts‐mrp.eu/download/AT_H_0270_001_PAR.pdf(last time accessed: April 18 2021).

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