Characterization of the 5‐HT 2C receptor agonist lorcaserin on efficacy and safety measures in a rat model of diet‐induced obesity-Reference-Cited by-同舟云学术

Characterization of the 5‐HT 2C receptor agonist lorcaserin on efficacy and safety measures in a rat model of diet‐induced obesity

Published:2014-11-07 Issue:1 Volume:3 Page:
ISSN:2052-1707
Container-title:Pharmacology Research & Perspectives
language:en
Short-container-title:Pharmacol Res Perspect

Author:

Higgins Guy A.¹²,Desnoyer Jill¹,Van Niekerk Annalise¹,Silenieks Leo B.¹,Lau Winnie¹,Thevarkunnel Sandy¹,Izhakova Julia¹,DeLannoy Ines A.M.¹,Fletcher Paul J.³⁴,DeLay Josepha⁵,Dobson Howard¹⁶⁷⁸

Affiliation:

1. InterVivo Solutions Inc. 120 Carlton St. Toronto Ontario Canada M5A 4K2

2. Department of Pharmacology & Toxicology University of Toronto Toronto Ontario Canada

3. Section of Biopsychology Clarke Division Centre for Addiction and Mental Health 250 College St. Toronto Ontario Canada M5T 1R8

4. Department of Psychiatry & Psychology University of Toronto Toronto Ontario Canada

5. Animal Health Laboratory U. Guelph Guelph Ontario Canada

6. CanCog Technologies Inc. 120 Carlton St. Toronto Ontario Canada M5A 4K2

7. Department of Clinical Studies University of Guelph Guelph Ontario Canada

8. Department of Biomedical Physics University of Western Ontario London Ontario Canada

Funder

InterVivo Solutions Inc.

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/prp2.84

Reference49 articles.

1. Arena Pharmaceuticals.2010.Briefing document: NDA 22‐529; Lorcaserin hydrochloride (APD356).

2. Serotonin and Appetite Regulation

3. Defining high-fat-diet rat models: metabolic and molecular effects of different fat types

4. Efficacy and safety of lorcaserin in obese adults: a meta-analysis of 1-year randomized controlled trials (RCTs) and narrative review on short-term RCTs

Cited by 27 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Reintroducing Fenfluramine as a Treatment for Seizures: Current Knowledge, Recommendations and Gaps in Understanding;Neuropsychiatric Disease and Treatment;2023-09

2. Fenfluramine: a plethora of mechanisms?;Frontiers in Pharmacology;2023-05-12

3. 5-HT2C Receptor Stimulation in Obesity Treatment: Orthosteric Agonists vs. Allosteric Modulators;Nutrients;2023-03-17

4. Bacillus amyloliquefaciens SC06 alleviates the obesity of ob/ob mice and improves their intestinal microbiota and bile acid metabolism;Food & Function;2022

5. Lorcaserin Inhibit Glucose-Stimulated Insulin Secretion and Calcium Influx in Murine Pancreatic Islets;Frontiers in Pharmacology;2021-11-05