Blockage of Src by Specific siRNA as a Novel Therapeutic Strategy to Prevent Destructive Repair in Steroid-Associated Osteonecrosis in Rabbits

Author:

Zheng Li-zhen1,Cao Hui-juan2,Chen Shi-hui1,Tang Tao13,Fu Wei-min14,Huang Le1,Chow Dick Ho Kiu1,Wang Yi-xiang5,Griffith James Francis5,He Wei6,Zhou Hong7,Zhao De-wei4,Zhang Ge1,Wang Xin-luan12,Qin Ling12

Affiliation:

1. Musculoskeletal Research Laboratory, Department of Orthopaedics & Traumatology; The Chinese University of Hong Kong; Hong Kong SAR PR China

2. Translational Medicine R&D Center, Institute of Biomedical and Health Engineering; Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences; Shenzhen PR China

3. Department of Obstetrics and Gynaecology; The Chinese University of Hong Kong; Hong Kong SAR PR China

4. Department of Orthopaedics; Zhongshan Hospital of Dalian University; Dalian PR China

5. Department of Imaging and Interventional Radiology; The Chinese University of Hong Kong; Hong Kong SAR PR China

6. Department of Orthopaedics; The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine; Guangzhou PR China

7. Bone Research Program, ANZAC (Australian and New Zealand Army Corps.) Research Institute; University of Sydney; Sydney Australia

Publisher

Wiley

Subject

Orthopedics and Sports Medicine,Endocrinology, Diabetes and Metabolism

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