Multi‐omics analysis of hiPSCs‐derived HLCs matured on‐chip revealed patterns typical of liver regeneration

Author:

Danoy Mathieu12ORCID,Tauran Yannick13,Poulain Stéphane45ORCID,Jellali Rachid6,Bruce Johanna7,Leduc Marjorie7,Le Gall Morgane7,Gilard Francoise8,Kido Taketomo9,Arakawa Hiroshi10,Araya Karin10,Mori Daiki11,Kato Yukio10,Kusuhara Hiroyuki11,Plessy Charles4,Miyajima Atsushi9,Sakai Yasuyuki2,Leclerc Eric16ORCID

Affiliation:

1. CNRS UMI 2820, Laboratory for Integrated Micro Mechatronic Systems Institute of Industrial Science Tokyo Japan

2. Department of Chemical System Engineering, Graduate School of Engineering The University of Tokyo Tokyo Japan

3. Laboratoire des Multimatériaux et Interfaces, UMR CNRS 5615 Univ Lyon, Université Claude Bernard Lyon 1 Villeurbanne France

4. RIKEN Center for Integrative Medical Science Yokohama Kanagawa Japan

5. Biomedical Microsystems Lab Institute of Industrial Science, The University of Tokyo Tokyo Japan

6. Université de Technologie de Compiègne, CNRS, Biomechanics and Bioengineering Centre de Recherche Royallieu‐CS 60319‐60203 Compiègne Cedex Compiègne France

7. Plateforme 3P5 Proteomi'ic Université de Paris, Institut Cochin, INSERM, U1016, CNRS, UMR8104 22 rue Méchain Paris France

8. Plateforme Métabolisme Métabolome, Institute of Plant Sciences Paris‐Saclay (IPS2), CNRS, INRA Univ. Paris‐Sud, Univ. Evry, Univ. Paris‐Diderot, Univ. Paris Saclay Gif‐sur‐Yvette Cedex France

9. Laboratory of Stem Cell Therapy, Institute for Quantitative Biosciences The University of Tokyo Tokyo Japan

10. Laboratory of Molecular Pharmacokinetics, Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences Kanazawa University Kanazawa City Ishikawa Japan

11. Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences The University of Tokyo Tokyo Japan

Funder

Japan Society for the Promotion of Science

Ministry of Education, Culture, Sports, Science and Technology

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

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