Assessment of alcohol‐induced aggressive behavior in zebrafish (Danio rerio): A practical class

Author:

Lopes Andressa Rubim1,Leandro Luana Paganotto2,Mariano Maria Vitória Takemura2,Posser Thais2,Franco Jeferson2ORCID

Affiliation:

1. Post graduate Program in Physiological Sciences, Institute of Biological Sciences Universidade Federal do Rio Grande (FURG) Rio Grande Rio Grande do Sul Brazil

2. Oxidative Stress and Cell Signaling Research Group (GPEOSCEL) Universidade Federal do Pampa (UNIPAMPA), Campus São Gabriel São Gabriel Rio Grande do Sul Brazil

Abstract

AbstractEthanol (EtOH) is among the most consumed drugs in the world. The behavior of humans after ingestion of this drug is characteristic: At low doses it may be excitatory and at higher doses, it may induce depressant/sedative effects. Similar effects are observed in the zebrafish experimental model (Danio rerio), which has about 70% genetic similarity with humans and has been widely used in numerous research. With the objective of improving the learning of biochemistry students, this work aimed to develop a practical exercise in the laboratory for students to observe the behavioral repertoire of zebrafish under the effects of exposure to ethanol. Through this practical class, the students were able to observe the similarity of the behavior of the animal model with that of humans, showing its importance for the consolidation of knowledge, awakening in the students an interest in science and its applications in everyday life.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

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