Deletion of the Gly600 Residue ofAlicyclobacillus acidocaldarius Squalene Cyclase Alters the Substrate Specificity into that of the Eukaryotic-Type Cyclase Specific to (3S)-2,3-Oxidosqualene-Reference-Cited by-同舟云学术

Deletion of the Gly600 Residue ofAlicyclobacillus acidocaldarius Squalene Cyclase Alters the Substrate Specificity into that of the Eukaryotic-Type Cyclase Specific to (3S)-2,3-Oxidosqualene

Published:2004-12-10 Issue:48 Volume:116 Page:6868-6871
ISSN:0044-8249
Container-title:Angewandte Chemie
language:de
Short-container-title:Angew. Chem.

Author:

Hoshino Tsutomu,Shimizu Kunio,Sato Tsutomu

Publisher

Wiley

Subject

General Medicine

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5. Squalene–hopene cyclase: final deprotonation reaction, conformational analysis for the cyclization of (3R,S)-2,3-oxidosqualene and further evidence for the requirement of an isopropylidene moiety both for initiation of the polycyclization cascade and for the formation of the 5-membered E-ring

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