Scalable, Transparent, and Micro: 3D‐Printed Rapid Tooling for Injection Molded Microfluidics

Author:

Menezes Pedro Duarte1,Hunter Alysha1,Dickson Thomas1,Hecht Soren1,Kumar Charchit1,Busek Mathias23,Krauss Stefan23,Gadegaard Nikolaj1ORCID

Affiliation:

1. Division of Biomedical Engineering James Watt School of Engineering University of Glasgow University Avenue Glasgow G12 8QQ UK

2. Hybrid Technology Hub Centre of Excellence Institute of Basic Medical Science University of Oslo P.O. Box 1110 0317 Oslo Norway

3. Department of Immunology and Transfusion Medicine Oslo University Hospital P.O. Box 4950 0424 Oslo Norway

Abstract

The fast‐growing 3D printing industry is improving its hardware at an accelerated pace. This includes higher‐resolution printing combined with a wider range of photosensitive resins. The parallel development of rapid tooling (RT) for injection molding enables upscaling 3D‐printed designs. Within microfluidics, where prototyping and scalability are key, the development of 3D‐printed RT for injection molding can prove a competitive alternative to more traditional tooling methods. Herein, the dominating parameters impacting 3D‐printed RT for injection molding are investigated, enabling the delivery of durable, high‐resolution, and optically transparent microfluidics. It is found that reducing the sidewall waviness to 1.9 ± 0.4 μm and the interlocking angle to 1.9 ± 0.8° enhances the mold release success rate to 100 ± 0.0%. The surface roughness is reduced from 1.1 ± 0.1 μm to 0.2 ± 0.0 μm by increasing layer exposure during printing. In turn, this improves the optical transparency of molded replicas to >228 lp mm−1 line resolution and increased image contrast and amplitude. Ultimately, the established procedure proves capable of running a small‐scale production (≈500 parts) of a droplet generator with 50 μm channels, with a lead production time of under 3 h from computer‐aided design to a functional device.

Funder

Norges Forskningsråd

Novo Nordisk Fonden

Publisher

Wiley

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