Affiliation:
1. Institute of Physics of Advanced Materials Ufa University of Science and Technology 32 Zaki Validi St. Ufa 450076 Russia
2. Laboratory for Dynamics and Extreme Characteristics of Promising Nanostructured Materials Saint Petersburg State University 28 University Ave. St. Petersburg 198504 Russia
3. Department of Traumatology and Orthopaedics Bashkir State Medical University 2a Teatralnaya St. Ufa 450000 Russia
Abstract
Titanium and its alloys are popular materials for medical application, particularly in implant devices, where high mechanical properties and osseointegration are critical factors for successful implantation. In this work, the progress in the studies of nanostructured commercially pure Grade 4 titanium (nanoTi) is demonstrated, in which an ultrafine‐grained structure with nanoscale grain size is formed using severe plastic deformation processing. Nanostructured Grade 4 Ti has a very high strength, and its physical nature and strengthening mechanisms are analyzed herein. NanoTi proved also to have very high osseointegration during in vivo experiments. At the same time, the highest biofunctionality is demonstrated by the etched nanoTi samples with pronounced surface roughness, the latter being revealed from precise roughness measurements. The present study provided convincing evidence of accelerated bone formation on nanoTi, which is very promising for manufacture of dental and maxillofacial implants.
Funder
Russian Science Foundation
Megagrants