BioWeld® Tube and surgical glue for experimental sutureless venous microanastomosis

Author:

Schwaiger N1,Wu J2,Wright B3,Morrissey L4,Harris M5,Rohanizadeh R6

Affiliation:

1. Clinic for Hand-, Plastic- and Microsurgery Friederikenstift, Hanover, Germany

2. Victor Chang Cardiac Research Institute, University of Wollongong, Sydney, New South Wales, Australia

3. Eddyline, University of Wollongong, Sydney, New South Wales, Australia

4. Graduate School of Medicine, University of Wollongong, Sydney, New South Wales, Australia

5. TM Ventures, University of Sydney, Sydney, New South Wales, Australia

6. Faculty of Pharmacy, University of Sydney, Sydney, New South Wales, Australia

Abstract

Abstract Background The medial wall of mammalian veins is generally thin and fragile compared with the thick muscle seen in arteries. This makes venous microanastomoses time consuming and challenging. This study aimed to determine the feasibility and effectiveness of using the BioWeld® Tube in conjunction with a surgical glue (butyl-2-cyanoacrylate) in performing sutureless venous microanastomoses. Methods The feasibility and effectiveness of microvascular anastomoses in a rabbit jugular vein model were investigated in six animals, using the BioWeld® Tube in conjunction with butyl-2-cyanoacrylate surgical glue. Patency and tissue repair mechanisms at the anastomotic site were assessed 1 week after the procedure. Results All anastomoses remained patent at 1 week. Muscle necrosis occurred only in areas where the tissue was subject to the fold-and-bond procedure. Conclusion The study showed the feasibility and short-term effectiveness of the BioWeld® Tube in facilitating venous anastomoses.

Publisher

Oxford University Press (OUP)

Subject

Surgery

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