Role of theBrafV637E mutation in hepatocarcinogenesis induced by treatment with diethylnitrosamine in neonatal B6C3F1 mice

Author:

Yamamoto Masahiro1,Tanaka Hiroki2,Xin Bing1,Nishikawa Yuji1,Yamazaki Kosuke3,Shimizu Keiko2,Ogawa Katsuhiro1

Affiliation:

1. Department of Pathology; Asahikawa Medical University; Asahikawa Japan

2. Department of Forensic Medicine; Asahikawa Medical University; Asahikawa Japan

3. Department of Clinical Medicine; Surgery Area; Japanese Red Cross Hokkaido College of Nursing; Kitami Japan

Funder

Japanese Ministry of Education, Culture, Sports, Science, and Technology

Asahikawa Medical University Advanced Science Research Program

Publisher

Wiley

Subject

Cancer Research,Molecular Biology

Reference42 articles.

1. Epidemiology of hepatocellular carcinoma;Mittal;J Clin Gastroenterol,2013

2. Morphology and metastatic nature of induced hepatic nodular lesions in C57BL x C3H F1 mice;Vesselinovitch;Cancer Res,1978

3. Mutations in the ras proto-oncogene: Clues to etiology and molecular pathogenesis of mouse liver tumors;Maronpot;Toxicology,1995

4. Differential selection for B-raf and Ha-ras mutated liver tumors in mice with high and low susceptibility to hepatocarcinogenesis;Buchmann;Mutat Res,2008

5. Clinicopathological relevance of BRAF mutations in human cancer;Pakneshan;Pathology,2013

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