In silico analysis of mutations near S1/S2 cleavage site in SARS‐CoV‐2 spike protein reveals increased propensity of glycosylation in Omicron strain-Reference-Cited by-同舟云学术

In silico analysis of mutations near S1/S2 cleavage site in SARS‐CoV‐2 spike protein reveals increased propensity of glycosylation in Omicron strain

Published:2022-06-07 Issue:9 Volume:94 Page:4181-4192
ISSN:0146-6615
Container-title:Journal of Medical Virology
language:en
Short-container-title:Journal of Medical Virology

Author:

Beaudoin Christopher A.¹,Pandurangan Arun P.¹,Kim So Yeon¹,Hamaia Samir W.²,Huang Christopher L.‐H.²³,Blundell Tom L.¹,Vedithi Sundeep Chaitanya¹,Jackson Antony P.²

Affiliation:

1. Department of Biochemistry, Sanger Building University of Cambridge Cambridge United Kingdom

2. Department of Biochemistry, Hopkins Building University of Cambridge Cambridge United Kingdom

3. Physiological Laboratory University of Cambridge Cambridge United Kingdom

Funder

American Leprosy Missions

Antibiotic Research UK

Publisher

Wiley

Subject

Infectious Diseases,Virology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jmv.27845

Reference57 articles.

1. A new coronavirus associated with human respiratory disease in China

2. SARS-CoV-2 variants, spike mutations and immune escape

3. WingerA CaspariT.The spike of concern—the novel variants of SARS‐CoV‐2.Viruses.2021;13:1002.doi:10.3390/v13061002

4. Structure and Mutations of SARS-CoV-2 Spike Protein: A Focused Overview

5. Omicron and Delta variant of SARS‐CoV‐2: A comparative computational study of spike protein

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