MMP-3 (-1171 5A/6A; Lys45Glu) variants affect serum levels of matrix metalloproteinase (MMP)-3 and correlate with severity of COPD: A study of MMP-3, MMP-7 and MMP-12 in a Tunisian population

Author:

Bchir Sarra12,ben Nasr Hela13,Garrouch Abdelhamid4,ben Anes Amel1,Abbassi Ammar15,Tabka Zouhair1,Chahed Karim16

Affiliation:

1. Unité de recherche UR12ES06, Physiologie de l'Exercice et Physiopathologie: de l'Intégré au Moléculaire ‘Biologie, Médecine et Santé’; Université de Sousse, Faculté de Médecine de Sousse; Tunisia

2. Department of Biology; Institut Supérieur de Biotechnologie de Monastir, Université de Monastir; Tunisia

3. Department of Biology; Institut des Sciences Infirmières; Sousse Tunisia

4. Service de Pneumo-Allergologie; CHU Farhat Hached; Sousse Tunisia

5. District Medical du Centre; CNAM; Sousse Tunisia

6. Department of Biochemistry; Université de Sfax, Faculté des Sciences de Sfax; Tunisia

Funder

Ministry of Higher Education and Scientific Research (Tunisia)

Ministry of Higher Education

Publisher

Wiley

Subject

Genetics(clinical),Drug Discovery,Genetics,Molecular Biology,Molecular Medicine

Reference50 articles.

1. Alternative projections of mortality and disability by cause 1990-2020: Global burden of disease study;Murray;Lancet,1997

2. Prevalence of COPD and tobacco smoking in Tunisia - results from the BOLD study;Daldoul;Int J Environ Res Public Health,2013

3. Global Initiative for Chronic Obstructive Lung Disease Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease www.beneficenciaespanola.com.mx/Portals/0/SociedadMedica/

4. Matrix metalloproteinases, new insights into the understanding of neurodegenerative disorders;Kim;Biomol Ther (Seoul),2012

5. Matrix metalloproteinases as modulators of inflammation and innate immunity;Parks;Nat Rev Immunol,2004

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