What tool do undergraduate pharmacy students prefer when grading systematic review evidence: AMSTAR‐2 or ROBIS?

Author:

Lee Shaun W. H.123ORCID

Affiliation:

1. School of Pharmacy Monash University Malaysia Subang Selangor Malaysia

2. School of Pharmacy Taylor's University Subang Selangor Malaysia

3. Center for Global Health University of Pennsylvania Philadelphia Pennsylvania USA

Abstract

AbstractIntroductionWhile systematic reviews (SRs) are considered the highest form of evidence in the hierarchy, the quality and standard of reviews varies. Two quality assessment tools have been developed to assess the variation in such standards. This study compared the preference, validity, reliability, and applicability of using A Measurement Tool to Assess Systematic Reviews (AMSTAR‐2) and the Risk of Bias in Systematic Reviews (ROBIS) for critically appraising evidence by pharmacy students.Materials and MethodsStudents attended eight lectures on evidence‐based medicine. Students independently assessed two SRs using AMSTAR‐2 and ROBIS. The agreement between both tools were calculated using Spearman's test while interrater reliability was calculated using Fleiss' κ statistics.ResultsStudents reported a preference for the AMSTAR‐2 tool due to its clear and distinct rating criteria as well as guidance provided by the tool's developer. In comparison, students found the items on the ROBIS tool difficult to judge as it was subjective. A moderate agreement between both tools on the overall domain ratings was noted (Spearman rs = 0.60). There was slight agreement in the overall confidence using AMSTAR‐2 (κ = 0.05; 95% confidence interval [CI]: 0.01–0.12) and the overall domain in ROBIS (κ = 0.09; 95% CI: 0.01–0.16).ConclusionThe AMSTAR‐2 tool had a low level of concordance in ratings of review among students. However, the AMSTAR‐2 tool was preferred by students due to the clear guidance and ease of use.

Publisher

Wiley

Reference25 articles.

1. Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews

2. Limitations of A Measurement Tool to Assess Systematic Reviews (AMSTAR) and suggestions for improvement

3. AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both

4. ROBIS: a new tool to assess risk of bias in systematic reviews was developed;Whiting P;JCE,2016

5. Minor differences were found between AMSTAR 2 and ROBIS in the assessment of systematic reviews including both randomized and nonrandomized studies;Pieper D;JCE,2019

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