microRNA‐16‐5p‐containing exosomes derived from bone marrow‐derived mesenchymal stem cells inhibit proliferation, migration, and invasion, while promoting apoptosis of colorectal cancer cells by downregulating ITGA2-Reference-Cited by-同舟云学术

microRNA‐16‐5p‐containing exosomes derived from bone marrow‐derived mesenchymal stem cells inhibit proliferation, migration, and invasion, while promoting apoptosis of colorectal cancer cells by downregulating ITGA2

Published:2019-05-17 Issue:11 Volume:234 Page:21380-21394
ISSN:0021-9541
Container-title:Journal of Cellular Physiology
language:en
Short-container-title:J Cell Physiol

Author:

Xu Yan¹,Shen Liangfang¹,Li Fujun²,Yang Junwen²,Wan Xiaoping³,Ouyang Miao²^ORCID

Affiliation:

1. Department of Oncology Xiangya Hospital, Central South University Changsha People's Republic of China

2. Department of Gastroenterology Xiangya Hospital, Central South University Changsha People's Republic of China

3. Department of Hepatobiliary Surgery Xiangya Hospital, Central South University Changsha People's Republic of China

Funder

Natural Science Foundation of Hunan Province

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcp.28747

Reference35 articles.

1. Global patterns and trends in colorectal cancer incidence and mortality

2. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

3. MiR-16-5p targets SESN1 to regulate the p53 signaling pathway, affecting myoblast proliferation and apoptosis, and is involved in myoblast differentiation

4. Human MSCs promotes colorectal cancer epithelial–mesenchymal transition and progression via CCL5/β-catenin/Slug pathway

5. BMSCs-derived miR-223-containing exosomes contribute to liver protection in experimental autoimmune hepatitis

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