Synthesis of an Alkyne-Modified Bleomycin Disaccharide Precursor, Conversion to a 18 F-Labeled Radiotracer, and Preliminary in vivo-PET Imaging Studies-Reference-Cited by-同舟云学术

Synthesis of an Alkyne-Modified Bleomycin Disaccharide Precursor, Conversion to a 18 F-Labeled Radiotracer, and Preliminary in vivo-PET Imaging Studies

Published:2018-12-05 Issue:1 Volume:2019 Page:156-163
ISSN:1434-193X
Container-title:European Journal of Organic Chemistry
language:en
Short-container-title:Eur. J. Org. Chem.

Author:

Maity Sajal K.¹,Yim Cheng-Bin²,Jadhav Satish¹³,Verhassel Alejandra⁴,Tuomela Johanna⁴,Solin Olof¹⁵,Grönroos Tove J.⁵^ORCID,Virta Pasi¹^ORCID

Affiliation:

1. Department of Chemistry; University of Turku; 20014 Turku Finland

2. Turku PET Centre (Å)bo Akademi University; 20520 Turku Finland

3. Department of Cellular and Molecular Medicine; School of Medicine; University of California; 92093 San Diego, La Jolla CA USA

4. Department of Cell biology and Anatomy; Institute of Biomedicine; University of Turku; 20520 Turku Finland

5. Turku PET Centre; University of Turku; 20520 Finland

Funder

Academy of Finland

Publisher

Wiley

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/ejoc.201801488/fullpdf

Reference25 articles.

1. Carbohydrate Dependent Targeting of Cancer Cells by Bleomycin−Microbubble Conjugates

2. Selective Tumor Cell Targeting by the Disaccharide Moiety of Bleomycin

3. The Disaccharide Moiety of Bleomycin Facilitates Uptake by Cancer Cells

4. The Carbamoylmannose Moiety of Bleomycin Mediates Selective Tumor Cell Targeting

5. Modified Bleomycin Disaccharides Exhibiting Improved Tumor Cell Targeting

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