Molecular Tweezers Inhibit PARP‐1 by a New Mechanism-Reference-Cited by-同舟云学术

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Molecular Tweezers Inhibit PARP‐1 by a New Mechanism

Published:2017-04-20 Issue:16 Volume:2017 Page:2223-2229
ISSN:1434-193X
Container-title:European Journal of Organic Chemistry
language:en
Short-container-title:Eur. J. Org. Chem.

Author:

Wilch Constanze¹,Talbiersky Peter¹,Berchner‐Pfannschmidt Utta²,Schaller Torsten¹,Kirsch Michael³,Klärner Frank‐Gerrit¹,Schrader Thomas¹

Affiliation:

1. Faculty of Chemistry University of Duisburg‐Essen Universitätsstr. 7 45117 Essen Germany

2. Laboratory for Molecular Ophthalmology University Hospital Essen Hufelandstr. 55 45122 Essen Germany

3. Institute of Physiological Chemistry University Hospital Essen Hufelandstr. 55 45122 Essen Germany

Funder

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ejoc.201601596

Reference44 articles.

1. Reversible and Noncompetitive Inhibition of β-Tryptase by Protein Surface Binding of Tetravalent Peptide Ligands Identified from a Combinatorial Split-Mix Library

2. Reversible and Noncompetitive Inhibition of β-Tryptase by Protein Surface Binding of Tetravalent Peptide Ligands Identified from a Combinatorial Split-Mix Library

3. Biological Catalysis Regulated by Cucurbit[7]uril Molecular Containers

4. Sequence-Specific Inhibition of a Nonspecific Protease

5. Supramolecular Control of Enzyme Activity through Cucurbit[8]uril-Mediated Dimerization

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1. Molecular Tweezers: Supramolecular Hosts with Broad-Spectrum Biological Applications;Pharmacological Reviews;2022-12-22

2. Exploring the Binding Mechanism of a Supramolecular Tweezer CLR01 to 14-3-3σ Protein via Well-Tempered Metadynamics;Frontiers in Chemistry;2022-05-12

3. Specific inhibition of the Survivin–CRM1 interaction by peptide-modified molecular tweezers;Nature Communications;2021-03-08

4. Different Inhibitors of Aβ42-Induced Toxicity Have Distinct Metal-Ion Dependency;ACS Chemical Neuroscience;2020-06-19

5. Pharmaceutical Applications of Molecular Tweezers, Clefts and Clips;Molecules;2019-05-09

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