Formation of 10/12/14-Membered Rings is Favored over 5/6/7-Membered. An Unexpected Result from Oxazole Chemistry-Reference-Cited by-同舟云学术

Formation of 10/12/14-Membered Rings is Favored over 5/6/7-Membered. An Unexpected Result from Oxazole Chemistry

Published:2019-08-01 Issue:30 Volume:2019 Page:4962-4967
ISSN:1434-193X
Container-title:European Journal of Organic Chemistry
language:en
Short-container-title:Eur. J. Org. Chem.

Author:

Slobodyanyuk Evgeniy Y.¹²,Berezowska Yulia L.¹²,Solomin Vitaliy V.¹,Volochnyuk Dmitriy M.¹²,Rozhenko Alexander B.²,Ryabukhin Sergey V.¹³,Grygorenko Oleksandr O.¹³^ORCID

Affiliation:

1. Enamine Ltd.; Chervonotkatska Street 78 02094 Kyiv Ukraine

2. Institute of Organic Chemistry; National Academy of Sciences of Ukraine; Murmanska Street 5 02660 Kyiv Ukraine

3. Taras Shevchenko National University of Kyiv; Volodymyrska Street 60 01601 Kyiv Ukraine

Funder

Enamine Ltd.

Ministry of Education and Science of Ukraine

Publisher

Wiley

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/ejoc.201900914/fullpdf

Reference40 articles.

1. Recent advance in oxazole-based medicinal chemistry

2. A comprehensive review on biological activities of oxazole derivatives

3. DrugBank 4.0: shedding new light on drug metabolism

4. Discovery of VU0409551/JNJ-46778212: An mGlu5 Positive Allosteric Modulator Clinical Candidate Targeting Schizophrenia

5. Further optimization of the mGlu5 PAM clinical candidate VU0409551/JNJ-46778212: Progress and challenges towards a back-up compound

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