Synthesis of Epibatidine Analogues by Pyrrole Diels-Alder Reactions: Rapid Access to Azabicyclo[2.2.1]heptane and 3,8-Diazabicyclo[3.2.1]octane Scaffolds for Library Synthesis-Reference-Cited by-同舟云学术

Synthesis of Epibatidine Analogues by Pyrrole Diels-Alder Reactions: Rapid Access to Azabicyclo[2.2.1]heptane and 3,8-Diazabicyclo[3.2.1]octane Scaffolds for Library Synthesis

Published:2016-12-19 Issue:1 Volume:2017 Page:138-148
ISSN:1434-193X
Container-title:European Journal of Organic Chemistry
language:en
Short-container-title:Eur. J. Org. Chem.

Author:

Murray Alexander T.¹,Packard Emma¹,Nortcliffe Andrew¹^ORCID,Lewis William¹,Hamza Daniel²,Jones Geraint²,Moody Christopher J.¹^ORCID

Affiliation:

1. School of Chemistry; University of Nottingham; University Park NG7 2RD Nottingham UK

2. Sygnature Discovery, BioCity; Pennyfoot Street NG1 1GF Nottingham UK

Funder

Seventh Framework Programme

Publisher

Wiley

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Reference29 articles.

1. Classification of skin alkaloids from neotropical poison-dart frogs (dendrobatidae)

2. Epibatidine: a novel (chloropyridyl)azabicycloheptane with potent analgesic activity from an Ecuadoran poison frog

3. Total synthesis of epibatidine

4. A versatile total synthesis of epibatidine and analogs

5. The synthesis of (+)- and (–)-epibatidine

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The European Lead Factory: An updated HTS compound library for innovative drug discovery;Drug Discovery Today;2021-10

2. Development of an enolate alkynylation approach towards the synthesis of the taiwanschirin natural products;Chemical Science;2021

3. Nitrogen-Bridged, Natural Product Like Octahydrobenzofurans and Octahydroindoles: Scope and Mechanism of Bridge-Forming Reductive Amination via Caged Heteroadamantanes;European Journal of Organic Chemistry;2018-08-21

4. Diastereoselective Synthesis of Highly Substituted, Amino- and Pyrrolidino-Tetrahydrofurans as Lead-Like Molecular Scaffolds;Chemistry - A European Journal;2018-05-16

5. Densely functionalised spirocyclic oxetane-piperidine scaffolds for drug discovery;Bioorganic & Medicinal Chemistry;2018-02