Isotype dependent on-column non-reversible aggregation of monoclonal antibodies

Author:

Farys Monika1,Gibson Daniel1,Lewis Alan P.1,Lewis Will1,Kucia-Tran Richard1ORCID

Affiliation:

1. Biopharm Process Development; GlaxoSmithKline; GSK Medicine Research Centre; Stevenage United Kingdom

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Reference20 articles.

1. Antibody production;Birch;Advance Drug Delivery Reviews,2006

2. Protein aggregation and bioprocessing;Cromwell;The AAPS Journal,2006

3. The therapeutic monoclonal antibody market;Ecker;Bioprocess Technology Consultants mAbs,2015

4. Industrial purification of pharmaceutical antibodies: Development, operation, and validation of chromatography processes;Fahrner;Biotechnology and Genetic Engineering Reviews,2001

5. Conformational plasticity of IgG during protein A affinity chromatography;Gagnon;Journal of Chromatography A,2016

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