Recombinant horseradish peroxidase variants for targeted cancer treatment-Reference-Cited by-同舟云学术

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Recombinant horseradish peroxidase variants for targeted cancer treatment

Published:2016-03-15 Issue:6 Volume:5 Page:1194-1203
ISSN:2045-7634
Container-title:Cancer Medicine
language:en
Short-container-title:Cancer Med

Author:

Bonifert Günther¹,Folkes Lisa²,Gmeiner Christoph¹,Dachs Gabi³,Spadiut Oliver¹^ORCID

Affiliation:

1. Research Area Biochemical Engineering Institute of Chemical Engineering Vienna University of Technology Vienna Austria

2. Department of Oncology Oxford Institute for Radiation Oncology University of Oxford Northwood Middlesex U.K.

3. Mackenzie Cancer Research Group Department of Pathology University of Otago Christchurch New Zealand

Funder

Austrian Science Fund

Publisher

Wiley

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cam4.668

Reference51 articles.

1. Bernard W. andC.P.W.Stewart.2014.World Cancer Report.World Health Organization.

2. Targeted Enzyme Prodrug Therapies

3. Prodrugs for Targeted Tumor Therapies: Recent Developments in ADEPT, GDEPT and PMT

4. Development of a novel enzyme/prodrug combination for gene therapy of cancer: horseradish peroxidase/indole-3-acetic acid

5. Oxidative activation of indole-3-acetic acids to cytotoxic species— a potential new role for plant auxins in cancer therapy11Abbreviations: IAA, indole-3-acetic acid; HRP, horseradish peroxidase; TBA, thiobarbituric acid; MPO, myeloperoxidase; MOI, 3-methylene-2-oxindole; BSO, buthionine sulphoximine; GSH, glutathione; CEA, carcinoembryonic antigen; ADEPT, antibody directed enzyme prodrug therapy; PDEPT, polymer directed enzyme prodrug therapy; GDEPT, gene directed enzyme prodrug therapy; and PEG, polyethylene glycol.

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