Empirical Bayes estimation of the selected treatment mean for two‐stage drop‐the‐loser trials: a meta‐analytic approach
Author:
Affiliation:
1. MRC Biostatistics Unit Hub for Trials Methodology Research Cambridge U.K.
2. Competence Center for Clinical Trials Bremen, Faculty 3 University of Bremen Bremen Germany
3. Novartis Pharma AG CH‐4002 Basel Switzerland
Funder
Medical Research Council
FWF
Publisher
Wiley
Subject
Statistics and Probability,Epidemiology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/sim.5920
Reference33 articles.
1. Drop-the-Losers Design: Normal Case
2. Interval estimation for drop-the-losers designs
3. US Food and Drug Administration (FDA) 2010. Guidance for Industry: Adaptive Design Clinical Trials for Drugs and Biologics.
4. Two stage conditionally unbiased estimators of the selected mean
5. Extension of a Two-Stage Conditionally Unbiased Estimator of the Selected Population to the Bivariate Normal Case
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