Design and synthesis of new trehalose-conjugated pentapeptides as inhibitors of Aβ(1-42) fibrillogenesis and toxicity

Author:

De Bona Paolo,Laura Giuffrida Maria,Caraci Filippo,Copani Agata,Pignataro Bruno,Attanasio Francesco,Cataldo Sebastiano,Pappalardo Giuseppe,Rizzarelli Enrico

Publisher

Wiley

Subject

Organic Chemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,General Medicine,Biochemistry,Structural Biology

Reference32 articles.

1. The molecular pathology of Alzheimer's disease;Selkoe;Neuron,1991

2. Neurodegeneration induced by β-amyloid peptides in vitro: the role of peptide assembly state;Pike;J. Neurosci.,1993

3. The toxicity of the Alzheimer's β-amyloid peptide correlates with a distinct fiber morphology;Seilheimer;J. Struct. Biol.,1997

4. Secondary structure of amyloid β peptide correlates with neurotoxic activity in vitro;Simmons;Mol. Pharmacol.,1994

5. Vicious cycles within the neuropathophysiologic mechanisms of Alzheimer's disease;Standridge;Curr. Alzheimer Res.,2006

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