Breast cancer in East Africa: Prevalence and spectrum of germline <scp>SNV</scp> /indel and <scp>CNVs</scp> in <scp> <i>BRCA1</i> </scp> and <scp> <i>BRCA2</i> </scp> genes among breast cancer patients in Tanzania-Reference-Cited by-同舟云学术

Breast cancer in East Africa: Prevalence and spectrum of germline SNV /indel and CNVs in BRCA1 and BRCA2 genes among breast cancer patients in Tanzania

Published:2022-07-31 Issue:3 Volume:12 Page:3395-3409
ISSN:2045-7634
Container-title:Cancer Medicine
language:en
Short-container-title:Cancer Medicine

Author:

Rweyemamu Linus P.¹²^ORCID,Gültaşlar Büşra K.³^ORCID,Akan Gokce⁴⁵^ORCID,Dharsee Nazima⁶,Namkinga Lucy A.¹,Lyantagaye Sylvester L.¹²,Yazıcı Hülya³⁷^ORCID,Atalar Fatmahan⁵⁸^ORCID

Affiliation:

1. Department of Molecular Biology and Biotechnology University of Dar es Salaam Dar es Salaam Tanzania

2. Mbeya College of Health and Allied Sciences University of Dar es Salaam Mbeya Tanzania

3. Division of Cancer Genetics, Department of Basic Oncology, Institute of Oncology Istanbul University Istanbul Turkiye

4. DESAM Research Institute Near East University Nicosia Cyprus

5. MUHAS Genetic Laboratory, Department of Biochemistry Muhimbili University of Health and Allied Sciences Dar es Salaam Tanzania

6. Academic, Research and Consultancy Unit Ocean Road Cancer Institute Dar es Salaam Tanzania

7. Department of Medical Biology and Genetics, Faculty of Medicine Istanbul Arel University Istanbul Turkiye

8. Department of Rare Diseases, Child Health Institute Istanbul University Istanbul Turkiye

Funder

University of Dar es Salaam

Publisher

Wiley

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cam4.5091

Reference46 articles.

1. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

2. Breast Cancer in Sub-Saharan Africa: Challenges and Opportunities to Reduce Mortality

3. KomenSG.Tanzania breast health care assessment: an assessment of breast cancer early detection diagnosis and treatment in Tanzania.2017.

4. Educational Opportunities for Down-Staging Breast Cancer in Low-Income Countries: an Example from Tanzania

5. Germline copy number variations in BRCA1/2 negative families: Role in the molecular etiology of hereditary breast cancer in Tunisia

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