Primary and secondary hemophagocytic lymphohistiocytosis have different patterns of T-cell activation, differentiation and repertoire

Author:

Ammann Sandra12,Lehmberg Kai3,zur Stadt Udo4,Janka Gritta3,Rensing-Ehl Anne1,Klemann Christian15,Heeg Maximilian15,Bode Sebastian15,Fuchs Ilka1,Ehl Stephan15,

Affiliation:

1. Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine; University of Freiburg; Germany

2. Faculty of Biology; University of Freiburg; Germany

3. Pediatric Hematology and Oncology; University Medical Center Hamburg Eppendorf; Germany

4. Center for Diagnostic; University Medical Center Hamburg Eppendorf; Germany

5. Center for Pediatrics; Department of Pediatric Hematology and Oncology, University Medical Center, University of Freiburg, Faculty of Medicine; University of Freiburg; Germany

Funder

Deutsche Forschungsgemeinschaft

Bundesministerium für Bildung und Forschung

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference47 articles.

1. Familial and acquired hemophagocytic lymphohistiocytosis;Janka;Annu. Rev. Med,2012

2. Inherited defects in lymphocyte cytotoxic activity;Pachlopnik Schmid;Immunol. Rev.,2010

3. Clinical, laboratory and molecular signs of immunodeficiency in patients with partial oculo-cutaneous albinism;Dotta;Orphanet J. Rare Dis.,2013

4. X-linked lymphoproliferative syndromes and related autosomal recessive disorders;Veillette;Curr. Opin. Allergy Clin. Immunol.,2013

5. Hemophagocytic lymphohistiocytosis. Report of 122 children from the International Registry. FHL Study Group of the Histiocyte Society;Arico;Leukemia.,1996

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