Sympathetic neural signaling via the β2-adrenergic receptor suppresses T-cell receptor-mediated human and mouse CD8+ T-cell effector function

Author:

Estrada Leonardo D.1,Ağaç Didem1,Farrar J. David1

Affiliation:

1. Department of Immunology; UT Southwestern Medical Center; Dallas TX USA

Funder

National Institute of Allergy and Infectious Diseases

National Institute of General Medical Sciences

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference45 articles.

1. Noradrenergic and peptidergic innervation of lymphoid tissue;Felten;J. Immunol.,1985

2. Noradrenergic sympathetic innervation of the spleen: I. Nerve fibers associate with lymphocytes and macrophages in specific compartments of the splenic white pulp;Felten;J. Neurosci. Res.,1987

3. An interleukin-1 beta-induced noradrenaline release in the spleen is mediated by brain corticotropin-releasing factor: an in vivo microdialysis study in conscious rats;Shimizu;Brain Behav. Immun.,1994

4. Correlations of norepinephrine release in the paraventricular nucleus with plasma corticosterone and leptin after systemic lipopolysaccharide: blockade by soluble IL-1 receptor;Francis;Brain Res.,2000

5. Sympathetic nervous system control of anti-influenza CD8+ T cell responses;Grebe;Proc. Natl. Acad. Sci. USA,2009

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