IL4-induced gene 1 is secreted at the immune synapse and modulates TCR activation independently of its enzymatic activity

Author:

Aubatin Aude12,Sako Nouhoum12,Decrouy Xavier32,Donnadieu Emmanuel456,Molinier-Frenkel Valérie127,Castellano Flavia128ORCID

Affiliation:

1. INSERM; U955, Equipe 09; Créteil France

2. Faculté de Médecine; Université Paris Est; Créteil France

3. INSERM; U955, Plateforme d′imagerie; Créteil France

4. INSERM; U1016, Institut Cochin; Paris France

5. CNRS; UMR8104; Paris France

6. Université Paris Descartes; Sorbonne Paris Cité; Paris France

7. AP-HP; Hôpital H. Mondor - A. Chenevier; Service d′Immunologie Biologique; Créteil France

8. AP-HP; Hôpital H. Mondor - A. Chenevier; Plateforme de Ressources Biologiques; Créteil France

Funder

Institut National de la Santé et de la Recherche Médicale

Fondation de la Recherche Médicale

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference35 articles.

1. T cell activation;Smith-Garvin;Annu. Rev. Immunol.,2009

2. An enigmatic tail of CD28 signaling;Boomer;Cold Spring Harb. Perspect. Biol.,2010

3. The immunological synapse;Dustin;Cancer Immunol. Res.,2014

4. Amino acid auxotrophy as a system of immunological control nodes;Murray;Nat. Immunol.,2016

5. An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells;Mezrich;J. Immunol.,2010

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