Temporal increase in thymocyte negative selection parallels enhanced thymic SIRPα+ DC function-Reference-Cited by-同舟云学术

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Temporal increase in thymocyte negative selection parallels enhanced thymic SIRPα+ DC function

Published:2016-09-06 Issue:10 Volume:46 Page:2352-2362
ISSN:0014-2980
Container-title:European Journal of Immunology
language:en
Short-container-title:Eur. J. Immunol.

Author:

Kroger Charles J.¹,Wang Bo¹,Tisch Roland¹²

Affiliation:

1. Department of Microbiology and Immunology; University of North Carolina at Chapel Hill School of Medicine; Chapel Hill NC USA

2. Lineberger Comprehensive Cancer Center; University of North Carolina at Chapel Hill School of Medicine; Chapel Hill NC USA

Funder

National Institutes of Health

Juvenile Diabetes Research Foundation

Lineberger Comprehensive Cancer Center, University of North Carolina

North Carolina Biotech Center Institutional

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/eji.201646354/fullpdf

Reference48 articles.

1. A central role for central tolerance;Kyewski;Annu. Rev. Immunol.,2006

2. T-cell apoptosis detected in situ during positive and negative selection in the thymus;Surh;Nature,1994

3. A defect in central tolerance in NOD mice;Kishimoto;Nat. Immunol.,2001

4. The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes;Pugliese;Nat. Genet.,1997

5. Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus;Vafiadis;Nat. Genet.,1997

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1. Encapsulation and immune protection for type 1 diabetes cell therapy;Advanced Drug Delivery Reviews;2024-04

2. Thymocyte regulatory variant alters transcription factor binding and protects from type 1 diabetes in infants;Scientific Reports;2022-08-19

3. Antibody-Mediated Targeting of a Hybrid Insulin Peptide Toward Neonatal Thymic Langerin-Positive Cells Enhances T-Cell Central Tolerance and Delays Autoimmune Diabetes;Diabetes;2022-08-01

4. Type 2 cytokines in the thymus activate Sirpα+ dendritic cells to promote clonal deletion;Nature Immunology;2022-05-30

5. Quantification of dendritic cell subsets in human thymus tissues of various ages;Immunity & Ageing;2021-11-18

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