Molecular characterization of an MLL1 fusion and its role in chromosomal instability-Reference-Cited by-同舟云学术

Molecular characterization of an MLL1 fusion and its role in chromosomal instability

Published:2018-12-31 Issue:2 Volume:13 Page:422-440
ISSN:1574-7891
Container-title:Molecular Oncology
language:en
Short-container-title:Mol Oncol

Author:

Parameswaran Sreejit¹,Vizeacoumar Frederick S.¹,Kalyanasundaram Bhanumathy Kalpana¹,Qin Fujun²,Islam Md. Fahmid¹,Toosi Behzad M.¹,Cunningham Chelsea E.¹,Mousseau Darrell D.³,Uppalapati Maruti C.¹,Stirling Peter C.⁴,Wu Yuliang⁵,Bonham Keith⁶,Freywald Andrew¹,Li Hui²,Vizeacoumar Franco J.¹⁶

Affiliation:

1. Department of Pathology and Laboratory Medicine, Cancer Cluster College of Medicine University of Saskatchewan Saskatoon Canada

2. Department of Pathology School of Medicine University of Virginia Charlottesville VA USA

3. Cell Signaling Laboratory Departments of Psychiatry and Physiology University of Saskatchewan Saskatoon Canada

4. Terry Fox Laboratory British Columbia Cancer Agency Vancouver Canada

5. Department of Biochemistry, Cancer Cluster College of Medicine University of Saskatchewan Saskatoon Canada

6. Cancer Research Saskatchewan Cancer Agency Saskatoon Canada

Funder

Saskatchewan Health Research Foundation

Natural Sciences and Engineering Research Council of Canada

Canadian Breast Cancer Foundation

Publisher

Wiley

Subject

Cancer Research,Genetics,Molecular Medicine,General Medicine,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/1878-0261.12423

Reference88 articles.

1. The role of HOX genes in normal hematopoiesis and acute leukemia

2. CENPA overexpression promotes genome instability in pRb-depleted human cells

3. Histone methylase MLL1 has critical roles in tumor growth and angiogenesis and its knockdown suppresses tumor growth in vivo

4. Molecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis

5. Epigenetic control of gene expression in leukemogenesis: Cooperation between wild type MLL and MLL fusion proteins

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