Dabrafenib inhibits the growth of BRAF‐WT cancers through CDK16 and NEK9 inhibition-Reference-Cited by-同舟云学术

Dabrafenib inhibits the growth of BRAF‐WT cancers through CDK16 and NEK9 inhibition

Published:2017-11-23 Issue:1 Volume:12 Page:74-88
ISSN:1574-7891
Container-title:Molecular Oncology
language:en
Short-container-title:Mol Oncol

Author:

Phadke Manali¹,Remsing Rix Lily L.²,Smalley Inna¹,Bryant Annamarie T.²,Luo Yunting³,Lawrence Harshani R.³,Schaible Braydon J.⁴,Chen Yian A.⁴,Rix Uwe²,Smalley Keiran S. M.¹⁵

Affiliation:

1. The Department of Tumor Biology The Moffitt Cancer Center & Research Institute Tampa FL USA

2. The Department of Drug Discovery The Moffitt Cancer Center & Research Institute Tampa FL USA

3. The Chemical Biology Core The Moffitt Cancer Center & Research Institute Tampa FL USA

4. The Department of Biostatistics and Bioinformatics The Moffitt Cancer Center & Research Institute Tampa FL USA

5. The Department of Cutaneous Oncology The Moffitt Cancer Center & Research Institute Tampa FL USA

Funder

National Institutes of Health

Melanoma Research Foundation

Publisher

Wiley

Subject

Cancer Research,Genetics,Molecular Medicine,General Medicine,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/1878-0261.12152

Reference40 articles.

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3. Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

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5. Application of Multiplexed Kinase Inhibitor Beads to Study Kinome Adaptations in Drug-Resistant Leukemia

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